Search results for "Regulatory systems"

showing 2 items of 2 documents

Model selection for factorial Gaussian graphical models with an application to dynamic regulatory networks.

2016

Abstract Factorial Gaussian graphical Models (fGGMs) have recently been proposed for inferring dynamic gene regulatory networks from genomic high-throughput data. In the search for true regulatory relationships amongst the vast space of possible networks, these models allow the imposition of certain restrictions on the dynamic nature of these relationships, such as Markov dependencies of low order – some entries of the precision matrix are a priori zeros – or equal dependency strengths across time lags – some entries of the precision matrix are assumed to be equal. The precision matrix is then estimated by l 1-penalized maximum likelihood, imposing a further constraint on the absolute value…

0301 basic medicineStatistics and ProbabilityFactorialDependency (UML)Computer scienceGaussianNormal Distributionpenalized inferencesparse networkscomputer.software_genreMachine learning01 natural sciencesNormal distribution010104 statistics & probability03 medical and health sciencessymbols.namesakeSparse networksGeneticsComputer SimulationGene Regulatory NetworksGraphical model0101 mathematicsgene-regulatory systemMolecular BiologyProbabilityMarkov chainModels GeneticPenalized inferencebusiness.industryModel selectiongraphical modelGene-regulatory systemsComputational Mathematics030104 developmental biologysymbolsA priori and a posterioriData miningArtificial intelligenceGraphical modelsSettore SECS-S/01 - StatisticabusinesscomputerNeisseriaAlgorithmsStatistical applications in genetics and molecular biology
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A note on validity in law and regulatory systems (position paper)

2012

This is position paper is located at the theoretical crossroads of several projects: CAPER, EU Grant Agreement 261712; CROWDSOURCING DER2012-39492-C02-0, SINTELNET FP7-ICT-2009-C-286380; CONSUMEDIA INNPACTO IPT-2011-1015-430000; CROWD-CRISSCONTROL IPT-2012-0968-390000. The notion of validity fulfils a crucial role in legal theory. The emerging Web 3.0 opens a new landscape where Semantic Web languages, legal ontologies, and the construction of Normative Multiagent Systems are built up to cover new regulatory needs. Conceptual models for complex regulatory systems shape the characteristic features of rules, norms and principles in different ways. This position paper outlines one of such mult…

Semantic Web (SW)HumanidadesComputingMilieux_LEGALASPECTSOFCOMPUTINGHª y Fª de la CienciaOntologiaFilosofía. EticaValidityLegal ontologiesNormative Multiagent Systems (nMAS)Regulatory systemsDret TeoriaCiencias básicas y experimentalesUNESCO::FILOSOFÍALegal theory:FILOSOFÍA [UNESCO]
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